Screening Adolescents for Type 2 Diabetes Mellitus in a Community Clinic

Sponsored by National Center for Research Resources (NCRR)

Phase Quota
Phase N/A

The purpose of this study is to evaluate the prevalence of Type 2 diabetes or impaired glucose tolerance in a subset of children 10-19 years of age in an inner city community clinic. The demographics of the clinic are 75% African American, 20% Hispanic, 5% other. African American and Hispanic patients have a higher prevalence of diabetes with significant morbidity, predominantly from microvascular and macrovascular disease. Obesity is commonly seen in patients with Type 2 diabetes and contributes to the underlying insulin resistance seen in the disease. Obesity is an increasing health problem among adolescents. Since Type 2 diabetes can be present for several years before diagnosis, it is worrisome that younger children will have undiagnosed Type 2 diabetes for years. This will increase the risk of earlier complications in these patients as young adults. We hypothesize that the occurrence of abnormal glucose metabolism in 400 children with either a history of obesity, family history of diabetes mellitus, or symptoms suggestive of diabetes mellitus will be higher than the general pediatric population. We believe that a family based educational program can reduce fasting plasma glucose.

Study Start Date: Not specified

Estimated Completion Date: Not specified

Specialties: Internal Medicine: Endocrinology Endocrinology: Diabetes Nurse Practitioner: Community Health,Education/Training,Preventive Medicine


  • Behavioral: Family based educational program

Inclusion criteria

  • Inclusion criteria for screening will be patients who have one of the following:
    • 120% of ideal body weight or BMI> 27
    • Weight greater than 75th percentile
    • Family history of type 2 diabetes in first or second degree relative
    • Acanthosis nigricans or skin tags as signs of insulin resistance
    • Symptoms of hyperglycemia (polyuria, polydipsia, polyphagia, or recurrent infections)
    • Symptoms or signs of PCOS (hyperandrogenism, hirsutism, irregular menses)

Exclusion criteria

  • None

Study Locations And Contact Information

  • Duke University, Durham North Carolina
    Contact: Susan Spratt, MD 919-684-4090
  • Duke University, Durham North Carolina
    Contact: Diana McNeill, MD 919-684-6841

Feature this Clinical Trial

Get your trial in front of 1000s of physicians and patients.
Visit to find out how you can feature this clinical trial.