Multicenter prospective cohort study on current treatments of legg-calvé-perthes disease
Sponsored by Texas Scottish Rite Hospital for Children
Legg-Calvé-Perthes disease is a childhood hip disorder which is common enough to be a
significant public health problem (affects 1 in 740 boys between ages 0—14), but uncommon
enough to have a sufficient number of patients from a single institution to perform a
definitive prospective study comparing the results of current treatments. The present study
will establish a database of prospectively identified patients with Legg-Calvé-Perthes (LCP)
Disease and collect information regarding their presentation, treatment, and outcomes in the
course of receiving currently available treatments.
This study seeks to compare the outcomes of current treatments in the management of three
age groups (ages 6—8, 8—11, >11) of patients with Perthes disease at two- and five-year
followup. For each age group, two to three common treatment regimens currently used by
practicing pediatric orthopaedic surgeons will be compared. The intervention a patient
receives is determined through physician preference. Physicians pick an intervention for
each age group and treat each patient with the same intervention.
Study Start Date: August 2012
Estimated Completion Date: September 2023
Internal Medicine: Epidemiology Family Medicine: Epidemiology
Procedure: multiple epiphyseal drilling
Diagnosed with Legg-Calvé-Perthes disease
Between age 6-16
Patients with possible secondary femoral osteonecrosis if over the age of 11 due to trauma or corticosteroid therapy are also eligible
Patients with previous surgical treatment
Study Locations And Contact Information
The University of Alabama at Birmingham, Birmingham Alabama
Contact: Shawn Gilbert MD 205-975-7499 email@example.com
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