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Carotid atherosclerosis predicts blood pressure control in patients with hypertension: The Campania Salute Network Registry

Journal of the American Heart AssociationMancusi C, Manzi MV, de Simone G, et al. | January 22, 2022


Studies have revealed carotid plaque (CP) as a strong correlate of increased arterial stiffness, which influences blood pressure (BP) control over time, however, the 2018 European Society of Cardiology/European Society of Hypertension arterial hypertension guidelines do not recommend routine carotid ultrasound as a tool to identify hypertension‐mediated organ damage, unless clinically indicated. Researchers herein examined if evidence of CP at first visit could aid in predicting BP control during follow‐up.

  • From the CSN (Campania Salute Network) Registry, researchers retrieved data of 6,684 patients with hypertension who had complete carotid ultrasound examination and categorized them by the presence of CP at baseline.

  • At baseline, CP was more frequently recorded in participants (n = 3,061) who were male, older, had diabetes, and showed higher systolic BP, lower diastolic BP, worse lipid profile, and higher prevalence of left ventricular hypertrophy.

  • Analysis revealed that in treated patients with hypertension, the presence of CP was associated with suboptimal BP control during follow‐up; this was recorded independently of worse metabolic profile and presence of left ventricular hypertrophy.