Association between infancy infections and development of atopic dermatitis in early childhood
Journal of the European Academy of Dermatology and Venereology — Lin TL, Fan YH, Chang YL, et al. | January 25, 2022
i>NOTE, original article title: Early‐life infections in association with the development of atopic dermatitis in infancy and early childhood: A nationwide nested case–control study
In view of the implications of microbial dysbiosis in the development of atopic dermatitis (AD), researchers herein sought to determine the risk of development of AD following early-life infections.
Using Taiwan's National Health Insurance Research Database, researchers performed this population-based nested case–control study including a total of 5,454 AD patients and 16,362 control individuals without AD.
On multivariate analyses, AD development was observed in independent correlation with infectious diseases, skin infections and systemic antibiotic exposure before AD diagnosis.
Asthma, allergic rhinitis, intussusception and neonatal hyperbilirubinemia are the other independent risk factors.