Association of bariatric surgery with cancer incidence in patients with obesity and diabetes: Long-term results from the Swedish Obese Subjects Study
Diabetes Care — Sjöholm K, Carlsson LMS, Svensson PA, et al. | November 24, 2021
In order to determine the effect of bariatric surgery on cancer risk in patients with obesity and diabetes, researchers herein examined the long-term incidence of cancer after bariatric surgery and usual care among these patients in the matched prospective Swedish Obese Subjects (SOS) study.
A total of 701 patients with obesity and type 2 diabetes were analyzed at baseline, 393 of whom underwent bariatric surgery and 308 who received conventional obesity treatment.
The patients were followed up for a median time of 21.3 years (interquartile range 17.6–24.8 years, maximum 30.7 years).
The incidence rate for first-time cancer was 9.1 per 1,000 person-years vs 14.1 per 1,000 person-years in patients with obesity and diabetes treated with bariatric surgery vs usual obesity care, respectively.
Outcomes suggest that in patients with obesity and diabetes, bariatric surgery is linked with prevention of cancer.
Reduced cancer risk was recorded in correlation with durable diabetes remission.
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