Clinical outcomes of older adults listed for heart transplantation in the United States
Journal of the American Geriatrics Society — Jaiswal A, Gadela NV, Baran D, et al. | June 10, 2021
Researchers undertook this retrospective cohort study to determine whether older age (>70 years) should be a relative contraindication for heart transplantation. For this purpose, they assessed features as well as the results of patients with age ≥70 years listed for heart transplantation. They also investigated if survival after transplantation was inferior to younger counterparts. They analyzed adults (≥18 years) listed for heart transplantation in the scientific registry of transplant recipients between 2000 and 2018. Findings revealed similar post-transplant survival up to 5 years among patients of age ≥70 years when compared with younger recipients. Seemingly, lower risk features were present in older patients who underwent heart transplantation but they received hearts from higher risk donors. Overall, chronologic age alone should not be a contraindication for heart transplantation, although implementing careful patient selection criteria is recommended.