Socioeconomic indicators of treatment prognosis for adults with depression

JAMA PsychiatryScott Cunningham MD PhD, et al. | June 27, 2022



In addition to well-known prognostic factors for treatment response among patients with depression, such as a history of depression, severity and duration of depression, and co-morbidities, this study has expanded our understanding of the many factors that contribute to the overall response to treatment in patients with depression.

A literature search was conducted for studies (n=9) involving patients with unipolar depression (n=4864) who sought treatment from general practitioners. The primary outcome was persistent symptoms of depression 3-4 months after beginning treatment.

The depression symptom scale score was 28% and 18% higher for unemployed patients and patients who did not own a home, respectively. Financial strain and level of education were not associated with persistent depressive symptoms in treated patients.