Comparison of the efficacy of low‐intensity shock wave therapy and its combination with platelet‐rich plasma in patients with erectile dysfunction

AndrologiaGeyik S, et al. | August 06, 2021


This study’s findings demonstrate that combination treatment of low-intensity shock wave therapy (Li-SWT) with platelet-rich plasma (PRP) injections is not only safe for individuals with erectile dysfunction (ED) but also effective and safe in prolonging the intravaginal ejaculatory latency time (IELT).

  • This study included 93 patients who were subjected to Li-SWT only (Group 1) and 91 patients subjected to Li-SWT with PRP (Group 2).

  • It was shown that the analysis of the International Index of Erectile Function-Erectile Function Area (IIEF-EF) scores demonstrated a significant increase in both the groups post-treatment (Group 1: from 14.33 ± 4.39 to 23.8 ± 4.37, p = .001; Group 2: from 17.82 ± 3.44 to 26.3 ± 2.55, p = .001).

  • No statistically significant difference was found between them when the increase in the IIEF-EF scores was compared pre-and post-treatment between the groups concerning the ED grades.

  • Moreover, Group 2 presented 1.5–3.5 times (mean, 2.4) prolongation, while the intravaginal ejaculatory latency time (IELT) in successfully treated patients of Group 1 remained the same.

  • In addition, their mean IELT score indicated an increase from 2.2 (0.8–3.5) min to 5.3 (2.8–10.5) min.

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