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Predictive value of neutrophil-to-lymphocyte ratio in terms of need for intensive care unit and mortality in maintenance hemodialysis patients with COVID-19

Hemodialysis InternationalOguz EG, Yeter HH, Akcay OF, et al. | January 11, 2022


Researchers investigated whether neutrophil-to-lymphocyte ratio (NLR) could aid in predicting worse outcomes in maintenance hemodialysis (MHD) patients.

  • A multicentered retrospective study of 123 MHD patients who had received inpatient care due to COVID-19 infection.

  • COVID-19 infection linked with death of 28 (23%) patients with MHD.

  • Relative to survivors, nonsurvivors were significantly older and had higher rates of diabetes mellitus and coronary artery disease.

  • Following were identified as independent factors associated with mortality: age older than 60 years, higher ferritin, and NLR > 5.17.

  • Relative to C reactive protein and systemic inflammatory index, NLR had favorable predictive value in terms of need for ICU and mortality in MHD patients.

  • Determination of the poor prognosis with simple and easily applicable markers may aid in providing early supportive treatments and thereby reduce mortality in these patients.