Current and past infections of HBV do not increase mortality in patients with COVID-19

HepatologyYip TCF, Wong VWS, Lui GCY, et al. | June 24, 2021

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Using data from the Clinical Data Analysis and Reporting System, researchers conducted a territory-wide retrospective cohort study to compare the risk of acute liver injury and mortality in patients with COVID-19 and current, past, and no HBV infection. Between January 23, 2020, and January 1, 2021, patients with COVID-19 were identified. Patients with hepatitis C or no HBsAg results were barred from participating. The final analysis included 5,639 patients (353 with current HBV infection, 359 with past HBV infection, and 4,927 with no known HBV exposure). Current HBV-infected patients were older and more likely to have cirrhosis compared with patients without known HBV exposure. Previous HBV-infected patients were the oldest, and they had a higher prevalence of diabetes and cardiovascular disease. Current or past HBV infections were not linked to more liver injury and mortality in COVID-19.

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