Positive effects of coffee on liver fibrosis in patients with chronic hepatitis B

Clinical NutritionBarré T, Fontaine H, Ramier C, et al. | January 25, 2022

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i>NOTE, original article title: Elevated coffee consumption is associated with a lower risk of elevated liver fibrosis biomarkers in patients treated for chronic hepatitis B (ANRS CO22 Hepather cohort)

Despite recent therapeutic advances, high risk of liver fibrosis, cirrhosis and liver cancer has been observed among patients chronically infected with hepatitis B virus (HBV). Researchers aimed at determining the socio-demographic and modifiable risk factors for significant fibrosis in chronic hepatitis B virus (HBV) patients by using cross-sectional data from the ANRS CO22 Hepather cohort.

  • A total of 2,065 untreated and 1,727 treated chronic HBV patients formed the study population.

  • As assessed by three non-invasive markers in treated chronic HBV patients, there appeared a consistent association of increased coffee consumption with a lower risk of significant liver fibrosis.

  • In real-world situations, immediate use of this result can be made, as patients at risk of advanced liver disease may benefit from increasing coffee consumption.

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