A time series analysis of detection and mortality of hepatitis C in Brazil, 2008–2018

BMC Infectious Diseasesde Brito RJVC, da Silva LF, Santos MB, et al. | January 25, 2022


In order to achieve the goal to eliminate hepatitis C virus (HCV) infection by 2030, efforts have been undertaken in Brazil. Considering the importance of understanding the disease profile in different regions of the country for designing strategies to fight the disease nationwide, researchers herein investigated the time trend of the incidence and mortality of hepatitis C in Brazil during the period from 2008 to 2018 according to sociodemographic and clinical characteristics.

  • Considering anti-HCV and HCV RNA positivity, there were 136,759 newly diagnosed cases of hepatitis C, and considering one or another positive test, there were 271,624 newly diagnosed cases during the period analyzed.

  • The Southeast (61%) and South (26.2%) Regions showed concentration of the majority of the records.

  • As per the joinpoint regression model, there appeared an increasing trend in the detection rate of hepatitis C in Brazil, but a decreasing trend in the mortality rate.

  • Overall there were disparities in the time trend of hepatitis C and in the sociodemographic and clinical characteristics in different regions of Brazil.

  • Considering these findings, strategies could be designed for the elimination of hepatitis C in Brazil, according to regional particularities.

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