Regular physical activity reduces the proinflammatory response in older women with diabetes and hypertension in the postmenopausal phase

Experimental GerontologyLopes DPS, Ribeiro IS, Santos DC, et al. | June 14, 2021

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Researchers conducted the study for analyzing the influence of physical activity on body composition, anthropometric parameters, lipid profile, and inflammatory markers of diabetic and hypertensive older postmenopausal women. The Family Health Units in Vitória da Conquista, Bahia, Brazil, assisted 163 women aged from 60 to 80 years who were diagnosed with T2DM and systemic arterial hypertension (SAH). The International Physical Activity Questionnaire was used to assess participants' physical activity levels, which were classified as active or sedentary. Active older women had improved body composition, lipid profile, and inflammatory balance. This was linked to a stronger correlation profile between these factors in active older women, which was not observed in sedentary older women. Furthermore, physical activity had a significant impact on IL-17A and the relationship between IL-10 and the other pro-inflammatory cytokines studied. As a result, physical activity is associated with a global improvement in T2DM and SAH risk factors, as well as a positive inflammatory modulation in diabetic and hypertensive older women.

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