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Neutrophil-lymphocyte ratio as a predictor of slow gait speed in older adults: The Rugao Longitudinal Aging Study

Experimental GerontologyGuo J, Zhang H, Li Y, et al. | June 10, 2021

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Researchers investigated whether and how neutrophil-to-lymphocyte ratio (NLR) levels were associated with risk of slow gait speed development among older adults. From the second wave of the Rugao Longitudinal Aging Study, a total of 1,753 participants (53.11% male, aged 60–92 years, with a mean age of 77.01 ± 4.27 years) were selected. Presence of slow gait speed was found in 394 persons in the cross-sectional analysis. After controlling for confounding factors, a significant as well as independent association of elevated NLR levels with an increased risk of slow gait speed was observed in older adults with and without comorbidities. Overall, slow gait speed risk in older adults was robustly and independently predicted by NLR, which affords an inexpensive and readily accessible inflammatory biomarker.

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