The relationship between use of alcohol, tobacco, and coffee in adolescence and mood disorders in adulthood

Acta Psychiatrica ScandinavicaScott Cunningham MD PhD, et al. | October 03, 2022



The current study demonstrated that alcohol consumption and cigarette smoking in adolescents, but not coffee consumption, are associated with mood disorders in later life. This finding supports longitudinal study findings that have shown alcohol consumption and cigarette smoking cause neurobiological changes in adolescents.

Data were extracted from The Northern Finland Birth Cohort 1986 Study. Alcohol consumption, cigarette smoking, and coffee consumption were determined for the participants (n=7660) at 16 years of age. The subsequent diagnoses of major depression disorder and bipolar disorder were recorded.

Of the 7660 patients in the current study, 11.5% and 1.1% were diagnosed with major depressive disorder and bipolar disorder by 33 years of age, respectively.

The mean number of cigarettes smoked per day (OR=1.23) and the volume of alcohol consumed (OR=1.22) at 16 years of age was associated with an increased risk of bipolar disorder in adulthood.

No association was shown between cigarette smoking and major depressive disorder.

No association between coffee consumption and mood disorders.