Long-term evolution of estimated glomerular filtration rate in patients with antiviral treatment for hepatitis C virus infection

Clinical Gastroenterology and HepatologyLiu CH, Lin JW, Liu CJ, et al. | February 07, 2022

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Researchers aimed at reporting on the long-term evolution of estimated glomerular filtration rate (eGFR) in patients receiving antiviral treatment for hepatitis C virus (HCV).

  • This cohort study involved a total of 1,987 patients with eGFR ≥ 15 mL/min/1.73m2 who received interferon (IFN) or direct-acting antiviral (DAA) treatment.

  • From the time point of sustained virologic response (SVR12), biannual assessment of the eGFR was performed by the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation.

  • Patients who achieved SVR12 with anti-HCV treatment had significantly improved long-term eGFR evolution and risk of ESRD.

  • Among patients who achieved SVR12, there was comparable eGFR evolution in those treated with IFN or DAA.

Read the full article on Clinical Gastroenterology and Hepatology

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