Nut consumption in association with overall mortality and recurrence/disease-specific mortality among long-term breast cancer survivors
International Journal of Cancer — Wang C, Gu K, Wang F, et al. | October 22, 2021
Long-term breast cancer survivors who consumed nuts were shown to have experienced better survival, especially disease-free survival (DFS).
Analysis of 3,449 long-term breast cancer survivors from the Shanghai Breast Cancer Survival Study, to assess the links of nut intake (including peanuts and tree nuts), evaluated at 5-year postdiagnosis, with overall survival (OS) and DFS.
At 5-year after dietary evaluation (ie, 10-year postdiagnosis), higher OS as well as DFS rates were evident in regular nut consumers.
Post-multivariable adjustment, a positive association of nut intake with OS and DFS was evident in a dose-response manner, with hazard ratios of 0.72 for OS and 0.48 for DFS, for those with greater than median nut intake vs nonconsumers.
No variation in the links was found by nut type.
The links were more obvious in those with a higher total energy intake for OS and in those with early stage (I-II) breast cancers for DFS.
There was no impact of estrogen receptor/progesterone receptor status or other known prognostic factors on the observed nut-DFS associations.