Prevalence and correlates of obsessive-compulsive symptoms in individuals with schizophrenia, schizoaffective disorder, or bipolar disorder

The Journal of Clinical PsychiatryScott Cunningham MD PhD, et al. | October 04, 2022



Obsessive-compulsive symptoms are common in patients with schizophrenia—up to 30% in some studies, and confirmed in the current study.

Data were extracted from the South London & Maudsley NHS Foundation Trust Biomedical Research Center case register, targeting patients diagnosed with schizophrenia, schizoaffective disorder, and bipolar disorder with obsessive-compulsive symptoms or obsessive-compulsive disorder.

Of the 21,551 patient records reviewed, 5179 (24.0%) had obsessive-compulsive symptoms and obsessive-compulsive disorder, and 2574 (11.9%) had obsessive-compulsive disorder.

Patients with schizophrenia, schizoaffective disorder, or bipolar and co-morbid obsessive-compulsive disorder were at increased risk for aggressive behavior (OR=1.18), cognitive problems (OR=1.21), hallucinations and delusions (OR=1.11), and physical problems (OR=1.17).