Behavioral, neurocognitive, polysomnographic and cardiometabolic profiles associated with obstructive sleep apnea in adolescents with ADHD

Journal of Child Psychology and PsychiatryPuzino K, Bourchtein E, Calhoun SL, et al. | July 28, 2021

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Researchers sought to explore the correlation of obstructive sleep apnea (OSA), defined as an apnea-hypopnea index of ≥ 2 events/hour, with sleep, neurobehavioral, and cardiometabolic outcomes in adolescents with attention-deficit/hyperactivity disorder (ADHD) from the general population. Four hundred twenty-one adolescents (16.9 ± 2.3 years, 53.9% male) underwent 9-hr polysomnography, neurobehavioral, and physical evaluation. When compared with ADHD-alone, adolescents with ADHD+OSA had phenotypic risk factors for OSA (ie, overweight/obesity, visceral adiposity, metabolic syndrome, and inflammation) but not worse neurobehavioral outcomes. While comorbidity is possible, such findings suggest that adolescents with suspicion of ADHD should be screened for OSA before receiving a diagnosis and starting psychoactive medication.

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