Efficacy of two-stage revision using a prosthesis of antibiotic-loaded acrylic cement spacer with or without cortical strut allograft in infected total elbow arthroplasty

Journal of Shoulder and Elbow SurgeryJoo M, et al. | June 28, 2021

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Researchers examined whether in infected total elbow arthroplasty, a self-manufactured prosthesis of antibiotic-loaded acrylic cement (PROSTALAC) spacer, with or without cortical strut allograft, would be efficacious. Among 18 patients (mean age, 66.9 years) who underwent two-stage revision arthroplasty for prosthetic infection following total elbow arthroplasty, they ensured infection control utilizing intravenous (IV) antibiotic therapy for 6 weeks or IV antibiotics for 4 weeks converting to oral antibiotics for 2 weeks following PROSTALAC insertion. In the management of elbow prosthetic infection, good clinical results and relatively low infection recurrence rates were obtained in correlation with undergoing two-stage revision arthroplasty using PROSTALAC spacer insertion in the first stage and cortical strut allograft in the second stage among patients with severe bone defect. However, a substantial complication rate was encountered.

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