The impact of comorbidities and their stacking on short- and long-term prognosis of patients over 50 with community-acquired pneumonia
BMC Infectious Diseases — Blanc E, Chaize G, Fievez S, et al. | September 15, 2021
The outcomes of hospitalized patients with community-acquired pneumonia (CAP) and pneumococcal infection CAP (P-CAP) are possibly influenced by specific comorbidities as well as by the number of combined comorbidities and the combination of at-risk (AR) and high-risk (HR) comorbidities.
From the 2014 French Information Systems Medicalization Program (PMSI), data of 182,858 patients was retrieved.
Of these patients, 149,555 patients aged ≥ 50 years (nonagenarians 17.8%) were hospitalized for CAP, including 8,270 with P-CAP.
Overall, 33.8% had ≥ 1 HR comorbidity and 90.5% had ≥ 1 AR comorbidity.
The most frequent AR comorbidity was cardiac diseases (all CAP: 77.4%).
Transfer in ICU was required for 5.4% of CAP cases and 19.4% for P-CAP.
There appeared an increase in short-term and 1-year in-hospital mortality rates mostly with age, and with the number of comorbidities and combination of AR and HR comorbidities, in addition of specific comorbidities.
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