Pulmonary embolism severity and in-hospital mortality in COVID vs non-COVID patients
European Journal of Internal Medicine — Miró O, Jiménez S, Llorens P, et al. | January 28, 2022
i>NOTE, original article title: Pulmonary embolism severity and in-hospital mortality: An international comparative study between COVID-19 and non-COVID patients
Patients with and without COVID were compared with respect to the severity of pulmonary embolism (PE). In addition, the association between severity and in-hospital-mortality was assessed.
A total of 549 COVID (71.3% PCR-confirmed) and 439 non-COVID patients with PE from 62 Spanish and 16 French emergency departments were analyzed.
PEs were of smaller size (43% vs 56% lobar or larger, 42% vs 35% segmental and 13% vs 9% subsegmental, respectively), right ventricular dysfunction (RVD) was less (22% vs 16%) and simplified Pulmonary Embolism Severity Index (sPESI) was lower among COVID patients vs non-COVID patients.
Although there were less severe PEs, risk of in-hospital mortality appeared to be higher among patients with COVID.
Findings overall suggest that in COVID patients, the usual tools for risk stratification, specifically the sPESI and RVD, are still valid, while there appeared no validity of the size of a PE.