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Association of physical activity and lower respiratory tract infection outcomes in patients with cardiovascular disease

Journal of the American Heart AssociationJung MH, Yi SW, An SJ, et al. | February 10, 2022


The dose‐response correlation between physical activity and lower respiratory tract infection (LoRI) outcomes was examined in patients with cardiovascular disease.

  • Using the Korean National Health Insurance data, researchers retrieved data of individuals aged 18 to 99 years (mean age, 62.6 ± 11.3 years; women, 49.6%) with cardiovascular disease who underwent health screening from January 1, 2009, to December 31, 2012 (n = 1,048,502) and were followed up until 2018 for mortality and until 2019 for hospitalization.

  • Self‐reported questionnaires were used to assess the amount of physical activity and categorization of physical activity was done into 5 groups: 0 (completely sedentary), < 500, 500 to 999, 1,000 to 1,499, and ≥ 1,500 metabolic equivalents of task min/wk.

  • Analyses revealed that patients with cardiovascular disease exhibit a reduced risk of mortality and hospitalization from LoRI in correlation with engaging in even a low level of physical activity compared with being completely sedentary, and incremental risk reduction occurs with increased physical activity.