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Comparison of SIRS criteria and qSOFA score for identifying culture-positive sepsis in the emergency department: A prospective cross-sectional multicentre study

BMJ OpenMignot-Evers L, Raaijmakers V, Buunk G, et al. | June 17, 2021

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Researchers conducted a prospective cross-sectional multicentre study with the aim to compare the daily practice of two emergency departments (ED) in the Netherlands, where systemic inflammatory response syndrome (SIRS) criteria and quick Sequential Organ Failure Assessment (qSOFA) score are employed differently as screening tools for culture-positive sepsis. They included a total of 760 patients with suspected infection who met SIRS criteria or had a qualifying qSOFA score. For each patient, calculation of SIRS criteria and qSOFA score was done. Relative to SIRS criteria, qSOFA score showed comparable efficacy in identifying culture-positive sepsis but performed significantly better for predicting in-hospital mortality and ICU admission. As per findings, there appears no longer necessity for SIRS criteria and qSOFA score is recommended as the standard for identifying culture-positive sepsis in the ED.

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