Social and health factors associated with unfavourable treatment outcome in adolescents and young adults with tuberculosis in Brazil: A national retrospective cohort study

The Lancet Global HealthChenciner L, Annerstedt KS, Pescarini JM, et al. | September 16, 2021


Treatment success rates in this national cohort of young people with tuberculosis in Brazil were lower than WHO End TB Strategy targets, with nearly a fifth of individuals reporting unfavorable treatment outcomes.

  • The primary factors associated with a negative result were homelessness, HIV, and illicit drug use.

  • In Brazil, efforts are needed to support this underserved group in order to achieve positive tuberculosis treatment outcomes.

  • Between January 1, 2015, and December 31, 2018, people aged 10 to 24 years (young people) with tuberculosis registered in Sistema de Informação de Agravos de Notificação (SINAN), were involved.

  • SINAN was notified of 67,360 young persons with tuberculosis, and 41,870 were included in the study.

  • Unfavorable treatment outcomes were experienced by 7,024 (17%) of the 41,870 persons involved in the study.

  • Young people who received government cash transfers had a lower risk of having a negative outcome.

Read the full article on The Lancet Global Health