Readmissions from venous thromboembolism after complex cancer surgery

JAMAMallick S, Aiken T, Varley P, et al. | January 28, 2022


Following complex cancer surgery, readmissions attributable to venous thromboembolism (VTE) continue to increase well beyond 30 days post-surgery. These readmissions vary by operation type and are linked with significant mortality and expenditure.

  • In this retrospective cohort study, a total of 126,104 patients from the Nationwide Readmissions Database who had VTE were included.

  • For the participants, 30-, 90-, and 180-day VTE–associated readmission rates were 0.6%, 1.1%, and 1.7%, respectively.

  • Independent factors linked with readmission were: type of operation, scores for severity and risk of mortality, age of 75 to 84 years (odds ratio [OR], 1.30), female gender (OR, 1.23), nonelective index admission (OR, 1.31), higher number of comorbidities (OR, 1.30), and having a major postoperative complication during the index admission (OR, 2.08).

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