Assessment of clinical outcomes among children and adolescents hospitalized with COVID-19 in 6 Sub-Saharan African countries
JAMA — Nachega JB, Sam-Agudu NA, Machekano RN, et al. | January 22, 2022
Researchers sought to report on the COVID-19 outcomes and associated factors among children and adolescents in sub-Saharan Africa, where preexisting comorbidities are prevalent.
Performing a retrospective record review of data from 25 hospitals in the Democratic Republic of the Congo, Ghana, Kenya, Nigeria, South Africa, and Uganda, a total of 469 children and adolescents hospitalized with COVID-19 were included in this cohort study.
A substantially higher morbidity and mortality was recorded in pediatric COVID-19 cases in African countries when compared with those in non-African settings and these were noted to be independently linked with age younger than 1 year and select noncommunicable disease comorbidities like hypertension, chronic lung disease, or a hematological disorder.
Given a high risk of adverse outcomes among pediatric cases of COVID-19 in African countries, COVID-19 vaccination and therapeutic interventions are required for African children and adolescents.
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