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Multivariate, transgenerational associations of the COVID-19 pandemic across minoritized and marginalized communities

JAMAYip SW, Jordan A, Kohler RJ, et al. | February 11, 2022


Researchers herein investigated the baseline pre–COVID-19 pandemic household factors that are linked with COVID-19 experiences, as defined by child and parent report, using a multivariate pattern-learning framework from the Adolescent Brain and Cognitive Development (ABCD) cohort.

  • In ABCD, which is an ongoing prospective longitudinal study of child and adolescent development in the United States, 11,875 youths were enrolled at age 9 to 10 years.

  • Researchers developed a multivariate pattern-learning strategy using nationally collected longitudinal profiling data from 9,267 families to determine factor combinations linked with transgenerational costs of the ongoing COVID-19 pandemic.

  • A total of 9,267 youth-parent dyads with more than 17,000 variables were included.

  • Social determinants of inequity, including household income and family structure, were identified as the primary associates of negative COVID-19 experiences, including elevated difficulties with school among children and concerns over racism linked with the COVID-19 pandemic among parents.

  • Findings reveal the necessity for community-level, transgenerational intervention strategies to combat the disproportionate burden of pandemics on minoritized and marginalized racial and ethnic populations.