Prevalence of Post-COVID-19 symptoms in hospitalized and non-hospitalized COVID-19 survivors: A systematic review and meta-analysis
European Journal of Internal Medicine — Fernández-de-las-Peñas C, Palacios-Ceña D, Gómez-Mayordomo V, et al. | June 17, 2021
A meta-analysis was conducted to examine the prevalence of post-COVID-19 symptoms in hospitalized and non-hospitalized patients recovered from COVID-19. Researchers carried out searches of MEDLINE, CINAHL, PubMed, EMBASE, and Web of Science databases, as well as medRxiv and bioRxiv preprint servers up to March 15, 2021. Peer-reviewed studies or preprints reporting data on post-COVID-19 symptoms collected by personal, telephonic or electronic interview were included. Random-effects models were used for meta-analytical pooled prevalence of each post-COVID-19 symptom, and I² statistics for heterogeneity. Results indicate that post-COVID-19 symptoms are present in more than 60% of patients infected by SARS-CoV‑2 in this meta-analysis. It was shown that fatigue and dyspnea were the most prevalent post-COVID-19 symptoms, especially 60 and ≥ 90 days after.