Behavioral Weight Loss as a Treatment for Migraine in Obese Women

Sponsored by The Miriam Hospital

Phase Quota
Phase N/A

The purpose of this pilot study is to compare the effects of a behavioral weight loss (BWL) intervention and a usual care control group on changes in headache frequency and severity per 28 days in women migraineurs who are obese.

Study Start Date: July 2012

Estimated Completion Date: June 2016

Specialties: Internal Medicine: Pain Management,Women`s Health Neurology: Headache,Pain Medicine Gastroenterology: Obesity Family Medicine: Pain Management,Women`s Health Endocrinology: Obesity Pain Management: Neurology


  • Other: Migraine Education
  • Behavioral: Behavioral weight loss
  • Behavioral: Behavioral Weight Loss Intervention

Inclusion criteria

  • Neurologist diagnosis of migraine (with or without aura) according to International Headache Society-based criteria
  • >= 2 migraine headaches per month as determined by participant's completion of a 4-wk
    headache diary at baseline
  • Overweight or obese (BMI >= 27 and <= 45)
  • No change in migraine or antidepressant medications for >= 2 months prior to study enrollment
  • No change in pattern of oral contraceptive use for >= 2 months prior to study enrollment
  • Able to walk at least 2 blocks in 10 minutes
  • Willing to be randomized to either the behavioral weight loss intervention or control group

Exclusion criteria

  • Main headache type other than migraine
  • secondary headache disorder
  • current participation in another weight loss program
  • taking medications that have weight loss side effects
  • in the judgment of investigators unlikely to adhere to the clinical trial prescriptions

Study Locations And Contact Information

  • The Miriam Hospital Weight Control and Diabetes Research Center, Providence Rhode Island
    Contact: Dale S Bond PhD 401-793-8950

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