Short Non-coding RNA Biomarkers of Predisposition to Ovarian Cancer

Sponsored by University of Virginia

Phase Quota
Phase N/A

The purpose of this study is to create new tests to identify biomarkers for ovarian cancer so that a screening test can be developed. For patients who have a diagnosis of ovarian Cancer, researchers will use blood samples before and after treatment to see if disease status can be determined by measuring the amount of biomarker.

Study Start Date: August 2010

Estimated Completion Date: June 2015

Specialties: Obstetrics & Gynecology: Gynecologic Oncology Oncology: Basic Science/Genetics,Gynecologic Oncology Pathology: Molecular Path/Genetics Physician Assistant: Hematology/Oncology,Obstetrics/Gynecology


No interventions cited

Inclusion criteria

  • Undergoing medical care at UVA
  • Up to date breast cancer screening
  • Subjects must fall into one of the following groups:
  • Women at increased risk of ovarian cancer based on family history, personal history, or genetic factors defined as either BRCA1 or BRCA2 mutations who still retain both fallopian tubes and both ovaries
  • Women at average risk for ovarian cancer
  • Women with known or suspected ovarian cancer who are undergoing evaluation and/or treatment at UVA Cancer Center

Exclusion criteria

  • History of prior malignancy within the last 10 years excluding cervical carcinoma in situ or basal cell carcinoma
  • Pregnancy (self reported)

Study Locations And Contact Information

  • University of Virginia, Charlottesville Virginia
    Contact: Heather Lothamer MSN 434-924-9924

Feature this Clinical Trial

Get your trial in front of 1000s of physicians and patients.
Visit to find out how you can feature this clinical trial.